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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRAF5 All Species: 22.42
Human Site: S457 Identified Species: 61.67
UniProt: O00463 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00463 NP_001029082.1 557 64406 S457 G D G S G R G S H L S L Y F V
Chimpanzee Pan troglodytes XP_001169985 557 64480 T457 G D G S G R G T H L S L Y F V
Rhesus Macaque Macaca mulatta B6CJY5 522 59446 S420 T M Q G E Y D S H L P W P F Q
Dog Lupus familis XP_537142 609 68722 T508 G D G S G K G T H L S L Y F V
Cat Felis silvestris
Mouse Mus musculus P70191 558 64126 T457 G D G S G K G T H L S L Y F V
Rat Rattus norvegicus B5DF45 530 60235 S428 T M Q G E Y D S H L P W P F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509429 560 65164 T459 G D G S G K G T H L S L Y F V
Chicken Gallus gallus
Frog Xenopus laevis Q6DJN2 556 63191 A438 L P S A Q R C A N Y I S L F V
Zebra Danio Brachydanio rerio Q6IWL4 542 61788 S428 T P S A P R C S N F I S L F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 23.1 71 N.A. 79.5 29.4 N.A. 74.8 N.A. 28.5 23.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 42.5 77.1 N.A. 89 47.4 N.A. 86 N.A. 49 42.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 26.6 86.6 N.A. 86.6 26.6 N.A. 86.6 N.A. 20 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 26.6 N.A. 100 N.A. 40 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 23 0 0 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % C
% Asp: 0 56 0 0 0 0 23 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 0 0 0 100 0 % F
% Gly: 56 0 56 23 56 0 56 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % I
% Lys: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 0 0 0 0 0 0 0 78 0 56 23 0 0 % L
% Met: 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 % N
% Pro: 0 23 0 0 12 0 0 0 0 0 23 0 23 0 0 % P
% Gln: 0 0 23 0 12 0 0 0 0 0 0 0 0 0 23 % Q
% Arg: 0 0 0 0 0 45 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 23 56 0 0 0 45 0 0 56 23 0 0 0 % S
% Thr: 34 0 0 0 0 0 0 45 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % W
% Tyr: 0 0 0 0 0 23 0 0 0 12 0 0 56 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _